The results of the fourth estimate of complete coverage of vaccination against covid-19 in Venezuela are reported, through questions included in a national sample survey. The survey was conducted between November 2 and 9, 2021 in population centers of 1,000 and more inhabitants. A total of 1,200 people aged 18 years and older were interviewed. Interviews were conducted in people’s homes. Complete vaccination coverage against covid-19 corresponds to 35.6% of the country’s total population. The age group with the highest complete coverage is those aged 50 and over (70.4%). Complete coverage in the Metropolitan District of Caracas (MDC) is 40.7%, in the main cities 32.6%, and in the rest of the country 35.6%. complete coverage is higher in the A-B socioeconomic level (45.0%). The population reporting that they do not have any vaccine dose, and want to be vaccinated, corresponds to 21.1%. And those who report that they are not vaccinated against covid-19, and do not want to be vaccinated, represent 9.6%. The full coverage reported indicates that Venezuela ranks 14th (out of 20 countries) in Latin America, when compared to the data available to date in Our World in Data.